1004 A novel use of adaptive servo ventilation for VNS-induced central sleep apnea in an adolescent with refractory epilepsy

Abstract Introduction Epilepsy is frequently encountered in the pediatric population and some patients are treated by stimulation of vagus nerve to reduce their seizure frequency. Vagus (VNS) may induce central sleep apnea. Adaptive servo ventilation a known treatment option for apnea certain adult with heart failure Cheyne-Stokes respiration but infrequently utilized population. Report case(s) A 17-year-old male history intractable generalized epilepsy, VNS placement, obstructive (OSA) (CSA) presented our tertiary care center management his disordered breathing. Initial breathing included CPAP OSA. After patient began have high residual apnea-hypopnea index on data card download CPAP. Polysomnography (PSG) was performed CSA events were noted that correlated firing. BiPAP titrated unsuccessful treating CSA. adjustment did not impact Repeat titration adaptive successfully OSA In follow up, tolerating ASV improvement nocturnal daytime functioning. Conclusion Central can be induced stimulation. This unique case documents successful an adolescent patient. Support (if any)